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Article

Molecular changes in the phosphatidylinositide 3-kinase (PI3K) pathway are common in gastric cancer.

Journal of surgical oncology - 1 Aug 2013

Tran Thang N, Brettingham-Moore Kate, Duong Cuong P, Mitchell Catherine, Clemons Nicholas J, Phillips Wayne A

Abstract excerpt

BACKGROUND AND OBJECTIVES: The phosphatidylinositide 3-kinase (PI3K) pathway is an important signalling pathway that is frequently activated in cancer cells. This has led to the emergence of PI3K inhibitors as potential new treatment modalities for many cancers. We have investigated the frequency of molecular changes in the PI3K pathway in gastric cancer. METHODS: A series of sixty one human gastric cancer...

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Share to Class I Phosphatidylinositol 3-Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Multiplex Polymerase Chain Reaction

Share to Phosphatidylinositol 3-Kinases

Share to PTEN Phosphohydrolase

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Source

Identifiers

PMID: 23813545
DOI: 10.1002/jso.23357

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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