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Article

Aurora A kinase regulates mammary epithelial cell fate by determining mitotic spindle orientation in a Notch-dependent manner.

Cell reports - 11 Jul 2013

Regan Joseph L, Sourisseau Tony, Soady Kelly, Kendrick Howard, McCarthy Afshan, Tang Chan, Brennan Keith, Linardopoulos Spiros, White Donald E, Smalley Matthew J

Abstract excerpt

Cell fate determination in the progeny of mammary epithelial stem/progenitor cells remains poorly understood. Here, we have examined the role of the mitotic kinase Aurora A (AURKA) in regulating the balance between basal and luminal mammary lineages. We find that AURKA is highly expressed in basa...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mammary Glands, Animal

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Source

Identifiers

PMID: 23810554
DOI: 10.1016/j.celrep.2013.05.044

Genes

AURKA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23810554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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