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Article

Similarities of molecular genetic changes in synchronous and metachronous colorectal cancers are limited and related to the cancers' proximities to each other.

The Journal of molecular diagnostics : JMD - 1 Sept 2013

Zauber Peter, Huang Jiaying, Sabbath-Solitare Marlene, Marotta Stephen

Abstract excerpt

Synchronous and metachronous colorectal cancers are distinct primary neoplasms diagnosed either simultaneously or sequentially in the same patient. Because they arise in a common genetic and environmental background, they offer a unique opportunity to study molecular genetic changes occurring during carcinogenesis. We evaluated tumors from 50 patients with synchronous and five additional patients with...

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Source

Identifiers

PMID: 23810502
DOI: 10.1016/j.jmoldx.2013.03.009

Genes

APC
BRAF
DCC
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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