A comparison of colon and rectal somatic DNA alterations.

doi:10.1007/DCR.0b013e3181a0e5df

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Article

A comparison of colon and rectal somatic DNA alterations.

Diseases of the colon and rectum - 1 Jul 2009

Slattery Martha L, Curtin Karen, Wolff Roger K, Boucher Kenneth M, Sweeney Carol, Edwards Sandra, Caan Bette J, Samowitz Wade

Abstract excerpt

PURPOSE: Differences in acquired mutations in colon and rectal tumors may account for differences in risk factors. In this study, we examined similarities and differences in somatic alterations in colon and rectal tumors. METHODS: Cases were identified from two large population-based case-control...

Topics

Adaptor Proteins, Signal Transducing
Adult
Aged
Biomarkers, Tumor
Case-Control Studies
Colonic Neoplasms
CpG Islands
Female
Genes, p53
Genes, ras
Genetic Markers
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Microsatellite Repeats

Middle Aged

Mutation

Proteoglycans

Proto-Oncogene Proteins B-raf

Source

Open in PubMed Open full text

Identifiers

PMID: 19571709
DOI: 10.1007/DCR.0b013e3181a0e5df
PMCID: PMC2718791

Genes

MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19571709-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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