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Article

A comparison of colon and rectal somatic DNA alterations.

Diseases of the colon and rectum - 1 Jul 2009

Slattery Martha L, Curtin Karen, Wolff Roger K, Boucher Kenneth M, Sweeney Carol, Edwards Sandra, Caan Bette J, Samowitz Wade

Abstract excerpt

PURPOSE: Differences in acquired mutations in colon and rectal tumors may account for differences in risk factors. In this study, we examined similarities and differences in somatic alterations in colon and rectal tumors. METHODS: Cases were identified from two large population-based case-control studies of colon cancer and rectal cancer. We sequenced Exons 5 to 8 of the p53 gene and Codons 12 and 13 of the...

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Identifiers

PMID: 19571709
DOI: 10.1007/DCR.0b013e3181a0e5df
PMCID: PMC2718791

Genes

MLH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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