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Article

Possible roles of the xenobiotic transporter P-glycoproteins encoded by the MDR1 3435 C>T gene polymorphism in differentiated thyroid cancers.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Ozdemir Semra, Uludag Ahmet, Silan Fatma, Atik Sinem Yalcintepe, Turgut Bulent, Ozdemir Ozturk

Abstract excerpt

BACKGROUND: P-glycoprotein (Pgp), encoded by the multidrug resistance 1 (MDR1) gene, is an efflux transporter which plays an important role in pharmacokinetics. The current preliminary study was designed to determine associations between a germ-line polymorphism in the MDR1 gene with differentiated thyroid carcinoma (DTC). MATERIALS AND METHODS: In the current case-control study, 60 differentiated thyroid cancers...

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Identifiers

PMID: 23803106
DOI: 10.7314/apjcp.2013.14.5.3213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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