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Article

ABCB1 genetic polymorphism and risk of upper aerodigestive tract cancers among smokers, tobacco chewers and alcoholics in an Indian population.

Pharmacogenetics and genomics - 1 Oct 2007

Sam Soya Sisy, Thomas Vinod, Sivagnanam Kumaran, Reddy Kanipakapatanam Sathyanarayana, Surianarayanan Gopalakrishnan, Chandrasekaran Adithan

Abstract excerpt

BACKGROUND AND OBJECTIVE: Upper aerodigestive tract (UADT) cancers are associated with the tobacco use and alcohol consumption. Certain toxins and carcinogens causing UADT cancers are found to be substrates of polymorphic ABCB1 gene encoded P-glycoprotein efflux pump. This study investigates the association between ABCB1 gene polymorphism at exon 26 (3435C>T) and risk to UADT cancers in Tamilians, a population of...

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Source

Identifiers

PMID: 17885624
DOI: 10.1097/FPC.0b013e3282c4b18a

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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