Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Pneumocystis Ace2 transcription factor regulates cell wall-remodeling genes and organism virulence.

The Journal of biological chemistry - 16 Aug 2013

Kottom Theodore J, Limper Andrew H

Abstract excerpt

Pneumocystis carinii (Pc) β-glucans are major components of the organism cell wall; yet, the regulation of Pc cell wall genesis and remodeling is not well understood. Ace2 transcription factors, which are present in many fungi, regulate glucanases and other enzymes needed for cell wall remodeling. The cloning and heterologous expression of PcAce2 in ace2Δ Saccharomyces cerevisiae demonstrated that PcAce2 can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida
Share to Cell Wall
Share to DNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to Gene Expression Regulation, Fungal

Share to Immunocompromised Host

Share to Neutropenia

Share to Pneumocystis carinii

Source

Open in PubMed Open full text

Identifiers

PMID: 23801335
DOI: 10.1074/jbc.M113.471243
PMCID: PMC3745336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Pneumocystis Ace2 transcription factor regulates cell wall-remodeling genes and organism virulence.PMID 23801335Read ↗

The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence.Semantic proximity Read ↗

Proteomic changes associated with inactivation of the Candida glabrata ACE2 virulence-moderating gene.Semantic proximity Read ↗

The RAM Network in Pathogenic FungiSemantic proximity Read ↗

Lung Epithelial Cells and Extracellular Matrix Components Induce Expression of Pneumocystis carinii STE20 , a Gene Complementing the Mating and Pseudohyphal Growth Defects of ste20 Mutant YeastSemantic proximity Read ↗

Inactivation of transcription factor gene ACE2 in the fungal pathogen Candida glabrata results in hypervirulence.Semantic proximity Read ↗

Candida albicans transcription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions.Semantic proximity Read ↗

Pneumocystis carinii BCK1 functions in a mitogen-activated protein kinase cascade regulating fungal cell-wall assembly.Semantic proximity Read ↗

The protein phosphatase 2C domain contributes to the pathobiological function of adenylyl cyclase in Cryptococcus neoformansSemantic proximity Read ↗

The histone acetyltransferase GcnE regulates conidiation and biofilm formation in Aspergillus fumigatusSemantic proximity Read ↗

A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development.Semantic proximity Read ↗

APP1 transcription is regulated by inositol-phosphorylceramide synthase 1-diacylglycerol pathway and is controlled by ATF2 transcription factor in Cryptococcus neoformans.Semantic proximity Read ↗

Toward an Integrated Model of Capsule Regulation in Cryptococcus neoformansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.