Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development.

PLoS genetics - 1 Apr 2015

Calderón-Noreña Diana M, González-Novo Alberto, Orellana-Muñoz Sara, Gutiérrez-Escribano Pilar, Arnáiz-Pita Yolanda, Dueñas-Santero Encarnación, Suárez M Belén, Bougnoux Marie-Elisabeth, Del Rey Francisco, Sherlock Gavin, d'Enfert Christophe, Correa-Bordes Jaime, de Aldana Carlos R Vázquez

Abstract excerpt

Candida albicans is a major invasive fungal pathogen in humans. An important virulence factor is its ability to switch between the yeast and hyphal forms, and these filamentous forms are important in tissue penetration and invasion. A common feature for filamentous growth is the ability to inhibit cell separation after cytokinesis, although it is poorly understood how this process is regulated developmentally. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyphae

Share to Protein Binding

Share to Protein Serine-Threonine Kinases

Share to Septins

Share to Signal Transduction

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25875512
DOI: 10.1371/journal.pgen.1005152
PMCID: PMC4398349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development.PMID 25875512Read ↗

The Ndr/LATS kinase Cbk1 regulates a specific subset of Ace2 functions and suppresses the hyphae-to-yeast transition in <i>Candida albicans</i>Semantic proximity Read ↗

The Cbk1-Ace2 axis guides Candida albicans from yeast to hyphae and back againSemantic proximity Read ↗

Hyphal chain formation in Candida albicans: Cdc28-Hgc1 phosphorylation of Efg1 represses cell separation genes.Semantic proximity Read ↗

Candida albicans transcription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions.Semantic proximity Read ↗

Proteomic changes associated with inactivation of the Candida glabrata ACE2 virulence-moderating gene.Semantic proximity Read ↗

Candida albicans hyphal initiation and elongation.Semantic proximity Read ↗

Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm FormationSemantic proximity Read ↗

The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence.Semantic proximity Read ↗

Hypoxia and Temperature Regulated Morphogenesis in Candida albicansSemantic proximity Read ↗

A Large-Scale Complex Haploinsufficiency-Based Genetic Interaction Screen in Candida albicans: Analysis of the RAM Network during MorphogenesisSemantic proximity Read ↗

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformansSemantic proximity Read ↗

Genetic determinants that permit growth without the core septin Cdc12 in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.