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The histone acetyltransferase GcnE regulates conidiation and biofilm formation in Aspergillus fumigatus

11 Apr 2019

Abstract excerpt

Histone modifications play a crucial role in eukaryotic gene regulation. The Spt-Ada-Gcn5-acetyltransferase (SAGA) complex controls histone acetylation, with Gcn5 (GcnE) acting as the acetyltransferase. In the Aspergillus species, GcnE has been shown to regulate asexual development and secondary metabolism. Apart from this, GcnE is required for pathogenicity in plant fungal pathogen A. flavus; however, the role...

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PMID: 31100153
DOI: 10.1093/mmy/myz043

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