Article
TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel.
Cells - 15 Jan 2021
Toft-Bertelsen Trine L, MacAulay Nanna
Abstract excerpt
The transient receptor potential vanilloid 4 channel (TRPV4) belongs to the mammalian TRP superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate array of stimuli, interacts with a multitude of proteins, and is modulated by a range of post-translational modifications, the majority of which we are only just beginning to understand. Not surprisingly, a great number of physiological...
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