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Article

Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1.

Pain - 1 Jul 2016

Wang Sen, Joseph John, Diatchenko Luda, Ro Jin Y, Chung Man-Kyo

Abstract excerpt

Transient receptor potential vanilloid 1 (TRPV1) is a polymodal receptor activated by capsaicin, heat, and acid, which plays critical roles in thermosensation and pain. In addition, TRPV1 also contributes to multiple pathophysiological states in respiratory, cardiovascular, metabolic, and renal systems. These contributions are further supported by evidence that variations in the human TRPV1 (hTRPV1) gene are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26967694
DOI: 10.1097/j.pain.0000000000000556
PMCID: PMC5512168

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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