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Impact of PTEN IVS4 Polymorphism (rs3830675) on Cancer Susceptibility: An Updated Meta-analysis.

Cancer genomics & proteomics - 1 Jan 2000

Wang Yue, Yang Helen, Luo J I, Ge Jinnian

Abstract excerpt

BACKGROUND/AIM: Phosphatase and tensin homolog (PTEN) acts as a tumor suppressor gene through the action of its phosphatase protein product. We performed a meta-analysis to evaluate their relationship. MATERIALS AND METHODS: A comprehensive database search was performed. Odds ratios (OR) with 95% confidence intervals (CI) were calculated to assess the association between PTEN IVS4 polymorphism and cancer....

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PMID: 26417029

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PTEN

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