Article
The association of phosphatase and tensin homolog deleted on chromosome 10 polymorphisms and lifestyle habits with colorectal cancer risk in a Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2014
Jing Fangyuan, Mao Yingying, Zhang Zhenyu, Li Yingjun, Cai Shaofang, Li Qilong, Ma Xinyuan, Jin Mingjuan, Chen Kun
Abstract excerpt
The PI3K signaling pathway plays an important role in the development of colorectal cancer (CRC) and other neoplasm. Somatic phosphatase and tensin homolog deleted on chromosome 10 (PTEN) mutations and deletions or epigenetic silencing have been observed in multiple tumor types including CRC. To assess the association of PTEN polymorphisms and lifestyle habits with CRC risk in Chinese population, we carried out a...
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