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Analysis of PTEN expression and promoter methylation in Uyghur patients with mild type 2 diabetes mellitus

1 Dec 2018

Abstract excerpt

Phosphatase and tension homolog deleted on chromosome 10 (PTEN) was considered as a promising target in type 2 diabetes mellitus (T2DM) because of its negative effects on insulin resistance. Alteration in DNA methylation is thought to play a role in the pathogenesis of T2DM. The aim of the present study was to quantitatively evaluate the promoter methylation of PTEN in Uyghur patients with mild T2DM. We evaluated...

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PMID: 30544451
DOI: 10.1097/md.0000000000013513

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