Article
Thrombocytosis as a response to high interleukin-6 levels in cGMP-dependent protein kinase I mutant mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2013
Zhang Lin, Lukowski Robert, Gaertner Florian, Lorenz Michael, Legate Kyle R, Domes Katrin, Angermeier Elisabeth, Hofmann Franz, Massberg Steffen
Abstract excerpt
OBJECTIVE: The purpose of this study was to investigate the influence of cGMP-dependent kinase I (cGKI) on platelet production. APPROACH AND RESULTS: We used hematology analyser to measure platelet counts in conventional cGKI-null mutants (cGKI(L1/L1)), gene-targeted cGKIα/β rescue mice (referred...
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