[Murine models of platelet diseases].

doi:10.1016/j.tracli.2007.04.010

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Article

[Murine models of platelet diseases].

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 May 2007

Lanza F

Abstract excerpt

Platelet-related diseases correspond to functional defects or abnormal production (thrombopoiesis) of hereditary and immunological origins. Recent progress in the manipulation of the mouse genome (transgenesis, gene inactivation or insertion) has resulted in the generation of numerous strains exhibiting defective platelet function or production. Some strains reproduce known hereditary diseases affecting...

Topics

Animals
Blood Platelet Disorders
Disease Models, Animal
Genome
Hemostasis
Mice
Mutation
Thrombocytopenia

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Open in PubMed

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PMID: 17500022
DOI: 10.1016/j.tracli.2007.04.010

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