Article
Modeling and dissection of longitudinal blood pressure and hypertension phenotypes in genetic epidemiological studies.
Genetic epidemiology - 1 Jan 2003
Bickeböller H, Barrett J H, Jacobs K B, Rosenberger A
Abstract excerpt
We discuss analyses of the Genetic Analysis Workshop 13 data from the Framingham Heart Study and simulations based on this study. We summarize analyses that investigated measures of systolic blood pressure or hypertension as the main phenotype, with the main focus being the modeling of this complex longitudinal phenotype. The approaches include familial aggregation methods and one-stage and two-stage linkage...
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