Article
SeqSIMLA: a sequence and phenotype simulation tool for complex disease studies.
BMC bioinformatics - 20 Jun 2013
Chung Ren-Hua, Shih Chung-Chin
Abstract excerpt
BACKGROUND: Association studies based on next-generation sequencing (NGS) technology have become popular, and statistical association tests for NGS data have been developed rapidly. A flexible tool for simulating sequence data in either unrelated case-control or family samples with different disease and quantitative trait models would be useful for evaluating the statistical power for planning a study design and...
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