Article

RAREsim: A simulation method for very rare genetic variants

2021-04-14

Abstract excerpt

Identification of rare variant associations is crucial to fully characterize the genetic architecture of complex traits and diseases. Essential in this process is the evaluation of novel methods in simulated data that mirrors the distribution of rare variants and haplotype structure in real data. Additionally, importing real variant annotation enables in silico comparison of methods that focus on putative causal v...

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Literature Corpus work: 1ca335df-b147-5586-9862-7758148c6b8c
DOI: 10.1101/2021.04.13.439644

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