Article
SimRare: a program to generate and analyze sequence-based data for association studies of quantitative and qualitative traits.
Bioinformatics (Oxford, England) - 15 Oct 2012
Li Biao, Wang Gao, Leal Suzanne M
Abstract excerpt
MOTIVATION: Currently, there is great interest in detecting complex trait rare variant associations using next-generation sequence data. On a monthly basis, new rare variant association methods are published. It is difficult to evaluate these methods because there is no standard to generate data and often comparisons are biased. In order to fairly compare rare variant association methods, it is necessary to...
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