Article
Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy.
BMC nephrology - 18 Jun 2013
Kavanagh David H, Savage David A, Patterson Christopher C, McKnight Amy Jayne, Crean John K, Maxwell Alexander P, McKay Gareth J
Abstract excerpt
BACKGROUND: Renal interstitial fibrosis and glomerular sclerosis are hallmarks of diabetic nephropathy (DN) and several studies have implicated members of the WNT pathways in these pathological processes. This study comprehensively examined common genetic variation within the WNT pathway for association with DN. METHODS: Genes within the WNT pathways were selected on the basis of nominal significance and...
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