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Article

Investigation of the association of BMP gene variants with nephropathy in Type 1 diabetes mellitus.

Diabetic medicine : a journal of the British Diabetic Association - 1 Jun 2010

McKnight A J, Pettigrew K A, Patterson C C, Kilner J, Sadlier D M, Maxwell A P

Abstract excerpt

AIMS: Diabetic nephropathy is a leading cause of end-stage renal disease. The transforming growth factor beta-bone morphogenic protein (BMP) pathway is implicated in the pathogenesis of diabetic nephropathy. The BMP2, BMP4 and BMP7 genes are located near linkage peaks for renal dysfunction, and we hypothesize that genetic polymorphisms in these biological and positional candidate genes may be risk factors for...

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Share to Bone Morphogenetic Protein 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20546278
DOI: 10.1111/j.1464-5491.2010.02976.x

Genes

BMP7
BMP2
BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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