Article
Association analysis of Notch pathway signalling genes in diabetic nephropathy.
Diabetologia - 1 Feb 2011
Kavanagh D, McKay G J, Patterson C C, McKnight A J, Maxwell A P, Savage D A
Abstract excerpt
AIMS/HYPOTHESIS: Several studies have provided compelling evidence implicating the Notch signalling pathway in diabetic nephropathy. Co-regulation of Notch signalling pathway genes with GREM1 has recently been demonstrated and several genes involved in the Notch pathway are differentially expressed in kidney biopsies from individuals with diabetic nephropathy. We assessed single-nucleotide polymorphisms (SNPs; n...
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