Article
Lack of association between the LRRK2 A419V variant and Asian Parkinson's disease.
Annals of the Academy of Medicine, Singapore - 1 May 2013
Gopalai Aroma Agape, Lim Shen Yang, Aziz Zariah Abdul, Lim Soo Kun, Tan Li Ping, Chong Yip Boon, Tan Chong Tin, Puvanarajah Santhi, Viswanathan Shanti, Kuppusamy Rishikesan, Tan Ai Huey, Lim Thien Thien, Eow Gaik Bee, Norlinah Mohamed Ibrahim, Li Hui Hua, Zhao Yi, Ahmad-Annuar Azlina
Abstract excerpt
INTRODUCTION: The G2385R and R1628P LRRK2 gene variants have been associated with an increased risk of Parkinson's disease (PD) in the Asian population. Recently, a new LRRK2 gene variant, A419V, was reported to be a third risk variant for PD in Asian patients. Our objective was to investigate th...
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