Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reward Sensitivity of ACC as an Intermediate Phenotype between DRD4-521T and Substance Misuse

29 Jan 2016

Abstract excerpt

The development and expression of the midbrain dopamine system is determined in part by genetic factors that vary across individuals such that dopamine-related genes are partly responsible for addiction vulnerability. However, a complete account of how dopamine-related genes predispose individuals to drug addiction remains to be developed. Adopting an intermediate phenotype approach, we investigated whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Hyperactivity Disorder
Share to Neural and Behavioral Psychology Studies
Share to Neurotransmitter Receptor Influence on Behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26601911
DOI: 10.1162/jocn_a_00905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reward Sensitivity of ACC as an Intermediate Phenotype between DRD4-521T and Substance MisusePMID 26601911Read ↗

Modulation of orbitofrontal-striatal reward activity by dopaminergic functional polymorphisms contributes to a predisposition to alcohol misuse in early adolescence.Semantic proximity Read ↗

Functional polymorphism of the mu-opioid receptor gene (OPRM1) influences reinforcement learning in humans.Semantic proximity Read ↗

Multilocus genetic composite reflecting dopamine signaling capacity predicts reward circuitry responsivity.Semantic proximity Read ↗

Variation in dopamine genes influences responsivity of the human reward system.Semantic proximity Read ↗

Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues.Semantic proximity Read ↗

The addictive brain: all roads lead to dopamine.Semantic proximity Read ↗

DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience.Semantic proximity Read ↗

Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)™ as a function of dopaminergic neurogenetics and brain functional connectivity linking all addictions under a common rubricSemantic proximity Read ↗

GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human AdolescentsSemantic proximity Read ↗

COMT Val(158) Met genotype is associated with reward learning: a replication study and meta-analysis.Semantic proximity Read ↗

Individual differences in extraversion and dopamine genetics predict neural reward responses.Semantic proximity Read ↗

Gene x abstinence effects on drug cue reactivity in addiction: multimodal evidence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.