Article
Variation within the serotonin (5-HT) 5-HT₂C receptor system aligns with vulnerability to cocaine cue reactivity.
Translational psychiatry - 11 Mar 2014
Anastasio N C, Liu S, Maili L, Swinford S E, Lane S D, Fox R G, Hamon S C, Nielsen D A, Cunningham K A, Moeller F G
Abstract excerpt
Cocaine dependence remains a challenging public health problem with relapse cited as a major determinant in its chronicity and severity. Environmental contexts and stimuli become reliably associated with its use leading to durable conditioned responses ('cue reactivity') that can predict relapse as well as treatment success. Individual variation in the magnitude and influence of cue reactivity over behavior in...
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