Article
Association of STAT6 and ADAM33 single nucleotide polymorphisms with asthma bronchiale and IgE level and its possible epigenetic background.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Sept 2012
Godava Marek, Kopriva Frantisek, Bohmova Jana, Vodicka Radek, Dusek Ladislav, Cvanova Michaela, Muzik Jan, Markova Marie, Schneiderova Eva, Vrtel Radek
Abstract excerpt
BACKGROUND: ADAM33 and STAT6 belong to the candidate genes that have been commonly associated with asthma, bronchial hyperresponsiveness or IgE levels. Our objective was to assess the association of 11 SNPs of the ADAM33 and 6 of the STAT6 and their haplotypes with IgE levels and asthma. We also evaluated the possible role of parental origin of haplotypes on IgE levels. METHODS: We enrolled 109 children with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
