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Article

Tangeretin sensitizes SGS1-deficient cells by inducing DNA damage.

Journal of agricultural and food chemistry - 3 Jul 2013

Chong Shin Yen, Wu Meng-Ying, Lo Yi-Chen

Abstract excerpt

Tangeretin, a polymethoxyflavone found in citrus peel, has been shown to have antiatherogenic, anti-inflammatory, and anticarcinogenic properties. However, the underlying target pathways are not fully characterized. We investigated the tangeretin sensitivity of yeast (Saccharomyces cerevisiae) mutants for DNA damage response or repair pathways. We found that tangeretin treatment significantly reduced (p < 0.05)...

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PMID: 23750935
DOI: 10.1021/jf401831e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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