Article
Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae.
Genetics - 1 Apr 2014
Eustice Moriah, Pillus Lorraine
Abstract excerpt
Chromatin organization and structure are crucial for transcriptional regulation, DNA replication, and damage repair. Although initially characterized in remodeling cell wall glucans, the β-1,3-glucanosyltransferase Gas1 was recently discovered to regulate transcriptional silencing in a manner separable from its activity at the cell wall. However, the function of Gas1 in modulating chromatin remains largely...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
