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Article

Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach.

PloS one - 1 Jan 2013

Hennings Johannes M, Kohli Martin A, Czamara Darina, Giese Maria, Eckert Anne, Wolf Christiane, Heck Angela, Domschke Katharina, Arolt Volker, Baune Bernhard T, Horstmann Sonja, Brückl Tanja, Klengel Torsten, Menke Andreas, Müller-Myhsok Bertram, Ising Marcus, Uhr Manfred, Lucae Susanne

Abstract excerpt

BACKGROUND: Data from clinical studies and results from animal models suggest an involvement of the neurotrophin system in the pathology of depression and antidepressant treatment response. Genetic variations within the genes coding for the brain-derived neurotrophic factor (BDNF) and its key receptor Trkb (NTRK2) may therefore influence the response to antidepressant treatment. METHODS: We performed a single and...

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Identifiers

PMID: 23750220
DOI: 10.1371/journal.pone.0064947
PMCID: PMC3672143

Genes

NTRK2
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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