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Article

Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients.

Archives of general psychiatry - 1 Apr 2010

Kohli Martin A, Salyakina Daria, Pfennig Andrea, Lucae Susanne, Horstmann Sonja, Menke Andreas, Kloiber Stefan, Hennings Johannes, Bradley Bekh B, Ressler Kerry J, Uhr Manfred, Müller-Myhsok Bertram, Holsboer Florian, Binder Elisabeth B

Abstract excerpt

CONTEXT: A consistent body of evidence supports a role of reduced neurotrophic signaling in the pathophysiology of major depressive disorder (MDD) and suicidal behavior. Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have been reported. OBJECTIVE: To determine whether the brain-derived neurotrophic factor (BDNF) gene or its high-affinity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20124106
DOI: 10.1001/archgenpsychiatry.2009.201
PMCID: PMC3696349

Genes

NTRK2
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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