Article
A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders.
The pharmacogenomics journal - 1 Apr 2008
Gratacòs M, Soria V, Urretavizcaya M, González J R, Crespo J M, Bayés M, de Cid R, Menchón J M, Vallejo J, Estivill X
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been studied extensively in relation to the susceptibility to mood disorders (MD), although it remains to be clarified whether BDNF is a susceptibility locus for MD phenotypes, including therapeutic response to antidepressants. We have performed a single-marker and haplotype association study of eight TagSNPs polymorphisms in the genomic region containing the BDNF gene...
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