Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for association between genetic variants of p75 neurotrophin receptor (p75NTR) gene and antidepressant treatment response in Chinese major depressive disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2008

Gau Yung-Tian A, Liou Ying-Jay, Yu Younger W-Y, Chen Tai-Jui, Lin Ming-Wei, Tsai Shih-Jen, Hong Chen-Jee

Abstract excerpt

The p75 neurotrophin receptor (p75(NTR)) is an essential component of neurotrophin system, and has been implicated in the pathogenesis of major depressive disorder (MDD) and in the mechanism of antidepressant action. This study aimed to delineate the association between phenotype (MDD susceptibility and antidepressant response) and genotype (p75(NTR) common genetic variants) in a Chinese population. A total of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents, Second-Generation
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Depressive Disorder, Major

Share to Genetic Variation

Share to Polymorphism, Single Nucleotide

Share to Receptor, Nerve Growth Factor

Share to Selective Serotonin Reuptake Inhibitors

Source

Identifiers

PMID: 18081157
DOI: 10.1002/ajmg.b.30646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for association between genetic variants of p75 neurotrophin receptor (p75NTR) gene and antidepressant treatment response in Chinese major depressive disorder.PMID 18081157Read ↗

The role of BDNF, NTRK2 gene and their interaction in development of treatment-resistant depression: data from multicenter, prospective, longitudinal clinic practice.Semantic proximity Read ↗

Family-based association study between brain-derived neurotrophic factor gene and major depressive disorder of Chinese descent.Semantic proximity Read ↗

A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders.Semantic proximity Read ↗

Support for association between the Ser205Leu polymorphism of p75(NTR) and major depressive disorder.Semantic proximity Read ↗

Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach.Semantic proximity Read ↗

A missense polymorphism (S205L) of the low-affinity neurotrophin receptor p75NTR gene is associated with depressive disorder and attempted suicide.Semantic proximity Read ↗

The associations of CNR1 SNPs and haplotypes with vulnerability and treatment response phenotypes in Han Chinese with major depressive disorder: A case-control association study.Semantic proximity Read ↗

Association study between 5-HT2A and NET gene polymorphisms and recurrent major depression disorder in Chinese Han population.Semantic proximity Read ↗

Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants.Semantic proximity Read ↗

Association between genetic polymorphism and antidepressants in major depression: a network meta-analysis.Semantic proximity Read ↗

Catecholamine pathway polymorphisms and antidepressant response.Semantic proximity Read ↗

No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.