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Article

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.

Biological psychiatry - 15 Aug 2005

Schumacher Johannes, Jamra Rami Abou, Becker Tim, Ohlraun Stephanie, Klopp Norman, Binder Elisabeth B, Schulze Thomas G, Deschner Monika, Schmäl Christine, Höfels Susanne, Zobel Astrid, Illig Thomas, Propping Peter, Holsboer Florian, Rietschel Marcella, Nöthen Markus M, Cichon Sven

Abstract excerpt

BACKGROUND: Previous genetic studies investigating a possible involvement of variations at the brain derived neurotrophic factor (BDNF) gene locus in major depressive disorder (MDD), bipolar affective disorder (BPAD), and schizophrenia have provided inconsistent results. METHODS: We performed single-marker and haplotype analyses using three BDNF polymorphisms in 2,376 individuals (465 MDD, 281 BPAD, 533...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16005437
DOI: 10.1016/j.biopsych.2005.04.006

Genes

BDNF

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Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.PMID 16005437Read ↗

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