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Article

A phylogenetic model for the detection of epistatic interactions.

Molecular biology and evolution - 1 Sept 2013

Nasrallah Chris A, Huelsenbeck John P

Abstract excerpt

Paired epistatic interactions, such as those in the stem regions of RNA, play an important role in many biological processes. However, unlike protein-coding regions, paired epistatic interactions have lacked the appropriate statistical tools for the detection of departures from selective neutrality. Here, a model is presented for the analysis of paired epistatic regions that draws upon the population genetics of...

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Identifiers

PMID: 23748181
DOI: 10.1093/molbev/mst108
PMCID: PMC3748351

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