Article
Localised JAK/STAT pathway activation is required for Drosophila wing hinge development.
PloS one - 1 Jan 2013
Johnstone Kirsty, Wells Richard E, Strutt David, Zeidler Martin P
Abstract excerpt
Extensive morphogenetic remodelling takes place during metamorphosis from a larval to an adult insect body plan. These changes are particularly intricate in the generation of the dipteran wing hinge, a complex structure that is derived from an apparently simple region of the wing imaginal disc. Using the characterisation of original outstretched alleles of the unpaired locus as a starting point, we demonstrate...
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