Article
Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway.
Mechanisms of development - 1 Sept 2002
Karsten Peter, Häder Sabine, Zeidler Martin P
Abstract excerpt
The suppressor of cytokine signalling (SOCS) gene family was originally identified as an immediate early response to cytokine signalling and function as negative regulators of the Janus kinase (JAK)/signal tranducers and activators of transcription (STAT) signal transduction pathway [Krebs and Hilton, J. Cell Sci. 113 (2000) 2813; Starr and Hilton, Int. J. Biochem. Cell Biol. 30 (1998) 1081]. Although key...
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