Article
slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development.
Development (Cambridge, England) - 1 Sept 1998
Theodosiou N A, Zhang S, Wang W Y, Xu T
Abstract excerpt
In the Drosophila leg disc, wingless (wg) and decapentaplegic (dpp) are expressed in a ventral-anterior and dorsal-anterior stripe of cells, respectively. This pattern of expression is essential for proper limb development. While the Hedgehog (Hh) pathway regulates dpp and wg expression in the an...
Topics
- Amino Acid Sequence
- Animals
- Body Patterning
- Cell Cycle Proteins
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Extremities
- Gene Expression Regulation, Developmental
- Genes, Insect
- Insect Proteins
- Molecular Sequence Data
- Mosaicism
- Mutation
- Phenotype
- Proto-Oncogene Proteins
- Restriction Mapping
- Sequence Homology, Amino Acid