Article
Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand.
Developmental biology - 15 Dec 2005
Hombría James Castelli-Gair, Brown Stephen, Häder Sabine, Zeidler Martin P
Abstract excerpt
The characterisation of ligands that activate the JAK/STAT pathway has the potential to throw light onto a comparatively poorly understood aspect of this important signal transduction cascade. Here, we describe our analysis of the only invertebrate JAK/STAT pathway ligands identified to date, the Drosophila unpaired-like family. We show that upd2 is expressed in a pattern essentially identical to that of upd and...
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