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Article

Clinical application of the CpG island methylator phenotype to prognostic diagnosis in neuroblastomas.

Journal of human genetics - 1 Jul 2013

Asada Kiyoshi, Abe Masanobu, Ushijima Toshikazu

Abstract excerpt

Clinical applications of aberrant DNA methylation to cancer diagnostics and therapeutics are accelerating. Especially, the CpG island methylator phenotype (CIMP), simultaneous methylation of multiple genes, provides information that cannot be obtained by other diagnostic methods and therapeutic opportunities. CIMP is known to be associated with poor or good prognosis depending upon cancer types. We identified...

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Identifiers

PMID: 23739128
DOI: 10.1038/jhg.2013.64

Genes

MYCN

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