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DNA Methylation Fingerprint of Neuroblastoma Reveals New Biological and Clinical Insights

12 Jun 2015

Abstract excerpt

AIM: To define the DNA methylation landscape of neuroblastoma and its clinicopathological impact. MATERIALS & METHODS: Microarray DNA methylation data were analyzed and associated with functional/regulatory genome annotation data, transcriptional profiles and clinicobiological parameters. RESULTS: DNA methylation changes in neuroblastoma affect not only promoters but also intragenic and intergenic regions at...

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PMID: 26067621
DOI: 10.2217/epi.15.49

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