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Article

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers

3 Oct 2012

Abstract excerpt

BACKGROUND: Accurate outcome prediction in neuroblastoma, which is necessary to enable the optimal choice of risk-related therapy, remains a challenge. To improve neuroblastoma patient stratification, this study aimed to identify prognostic tumor DNA methylation biomarkers. RESULTS: To identify genes silenced by promoter methylation, we first applied two independent genome-wide methylation screening methodologies...

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PMID: 23034519
DOI: 10.1186/gb-2012-13-10-r95

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