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Article

Identification of genes targeted by CpG island methylator phenotype in neuroblastomas, and their possible integrative involvement in poor prognosis.

Oncology - 1 Jan 2008

Abe Masanobu, Watanabe Naoko, McDonell Nathalie, Takato Tsuyoshi, Ohira Miki, Nakagawara Akira, Ushijima Toshikazu

Abstract excerpt

BACKGROUND/AIMS: CpG island (CGI) methylator phenotype (CIMP) is strongly associated with poor prognosis in neuroblastomas (NBLs; hazard ratios 7-22). Methylation of nonpromoter CGIs is useful to detect the presence of the CIMP, while the poor prognosis is considered to be caused by gene silencin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 18544995
DOI: 10.1159/000139124

Genes

CRYBA2
NPY
PCDHGC4
SPAG6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18544995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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