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Article

HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis.

PloS one - 1 Jan 2013

Balandraud Nathalie, Picard Christophe, Reviron Denis, Landais Cyril, Toussirot Eric, Lambert Nathalie, Telle Emmanuel, Charpin Caroline, Wendling Daniel, Pardoux Etienne, Auger Isabelle, Roudier Jean

Abstract excerpt

OBJECTIVE: To provide a table indicating the risk for developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis (RA) according to one's HLA-DRB1 genotype. METHODS: We HLA-DRB1 genotyped 857 patients with ACPA positive RA and 2178 controls from South Eastern and Eastern France and calculated Odds Ratios (OR) for developing RA for 106 of 132 possible genotypes accounting for 97% of...

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Identifiers

PMID: 23737967
DOI: 10.1371/journal.pone.0064108
PMCID: PMC3667843

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