The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project.

doi:10.1038/ejhg.2013.116

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Article

The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project.

European journal of human genetics : EJHG - 1 Feb 2014

Medway Christopher, Combarros Onofre, Cortina-Borja Mario, Butler Helen T, Ibrahim-Verbaas Carla A, de Bruijn Renée F A G, Koudstaal Peter J, van Duijn Cornelia M, Ikram M Arfan, Mateo Ignacio, Sánchez-Juan Pascual, Lehmann Michael G, Heun Reinhard, Kölsch Heike, Deloukas Panos, Hammond Naomi, Coto Eliecer, Alvarez Victoria, Kehoe Patrick G, Barber Rachel, Wilcock Gordon K, Brown Kristelle, Belbin Olivia, Warden Donald R, Smith A David, Morgan Kevin, Lehmann Donald J

Abstract excerpt

Epistasis between interleukin-10 (IL10) and aromatase gene polymorphisms has previously been reported to modify the risk of Alzheimer's disease (AD). However, although the main effects of aromatase variants suggest a sex-specific effect in AD, there has been insufficient power to detect sex-speci...

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PMID: 23736221
DOI: 10.1038/ejhg.2013.116
PMCID: PMC3895636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23736221-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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