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Article

Bridging the Gap between Statistical and Biological Epistasis in Alzheimer’s Disease

1 Jan 2015

Abstract excerpt

Alzheimer's disease affects millions of people worldwide and incidence is expected to rise as the population ages, but no effective therapies exist despite decades of research and more than 20 known disease markers. Research has shown that Alzheimer's disease's missing heritability remains extensive with an estimated 25% of phenotypic variance unexplained by known variants. The missing heritability may be...

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PMID: 26075270
DOI: 10.1155/2015/870123

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