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Article

Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women.

Dementia and geriatric cognitive disorders - 1 Jan 2009

Corbo Rosa Maria, Gambina Giuseppe, Ulizzi Laura, Moretto Giuseppe, Scacchi Renato

Abstract excerpt

BACKGROUND/AIMS: There is evidence for a higher prevalence of Alzheimer's disease (AD) in women, but whether this is due to their longer life expectancy or to biological gender-specific risk factors is unclear. One likely contributing factor is the reduced estrogen neuroprotective action following menopause. In this context, an AD risk gene could be CYP19, encoding aromatase, an enzyme involved in estrogen...

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Identifiers

PMID: 19478482
DOI: 10.1159/000221832

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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