Article
Association of the aromatase gene with Alzheimer's disease in women.
Neuroscience letters - 14 Jan 2010
Butler Helen T, Warden Donald R, Hogervorst Eva, Ragoussis Jiannis, Smith A David, Lehmann Donald J
Abstract excerpt
Associations have been reported of aromatase polymorphisms with Alzheimer's disease (AD). We studied nine polymorphisms in 207 cases of AD, 23 cases of mild cognitive impairment (MCI) and 233 controls, all from the OPTIMA cohort. We replicated two reported associations and found others. Our findings were consistent between AD and MCI. Further, our results were sex-specific, i.e. there were significant...
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