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Article

Using the Cre-lox system to randomize target gene expression states and generate diverse phenotypes.

Biotechnology and bioengineering - 1 Oct 2013

Niesner Bradley, Maheshri Narendra

Abstract excerpt

Modifying the expression of multiple genes enables both deeper understanding of their function and the engineering of complex multigenic cellular phenotypes. However, deletion or overexpression of multiple genes is typically laborious and involves multiple sequential genetic modifications. Here w...

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Identifiers

PMID: 23733452
DOI: 10.1002/bit.24952
PMCID: PMC4264681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23733452-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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