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Article

Lox'd in translation: contradictions in the nomenclature surrounding common lox-site mutants and their implications in experiments.

Microbiology (Reading, England) - 1 Jan 2021

Shaw Daniel, Serrano Luis, Lluch-Senar Maria

Abstract excerpt

The Cre-Lox system is a highly versatile and powerful DNA recombinase mechanism, mainly used in genetic engineering to insert or remove desired DNA sequences. It is widely utilized across multiple fields of biology, with applications ranging from plants, to mammals, to microbes. A key feature of this system is its ability to allow recombination between mutant lox sites. Two of the most commonly used mutant sites...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33284099
DOI: 10.1099/mic.0.000997
PMCID: PMC8116776

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